A spectroscopic liquid biopsy for the earlier detection of multiple cancer types

JM Cameron, A Sala, G Antoniou, PM Brennan, HJB Butler, JJA Conn, S Connal, T Curran, MG Hegarty, RG Hardy, D Orringer, DS Palmer, BR Smith, MJ Baker

Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan, DS Palmer, JD Palmer, H Perlow, MJ Baker

Rapid Spectroscopic Liquid Biopsy for the Universal Detection of Brain Tumours

AG Theakstone, PM Brennan, MD Jenkinson,...
Cancers 13(15): 3851

Interrogation of IDH1 status in gliomas by Fourier transform infrared spectroscopy

JM Cameron, JJA Conn, C Rinaldi, A Sala, PM Brennan, MD Jenkinson, ...
Cancers 12 (12), 3682

Liquid biopsy for cancer diagnosis using vibrational spectroscopy: systematic review

DJ Anderson, RG Anderson, SJ Moug, MJ Baker
BJS open 4 (4), 554

Vibrational spectroscopic analysis and quantification of proteins in human blood plasma and serum

JM Cameron, C Bruno, DR Parachalil, MJ Baker, F Bonnier, HJ Butler, ...
Vibrational Spectroscopy in Protein Research, 269-314

Developing IR spectroscopic detection for stratifying brain tumour patients

JM Cameron, HJ Butler, BR Smith, ...
Analyst 144 (22), 6736-6750

Health economic evaluation of a serum- based blood test for brain tumour diagnosis: exploration of two clinical scenarios

E Gray, HJ Butler, R Board, PM Brennan, AJ Chalmers, T Dawson, ...
BMJ open 8 (5)

A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of brain tumors

K Spalding, R Board, T Dawson, MD Jenkinson, MJ Baker
Brain and behavior 6 (9), e00502

Brain tumour differentiation: rapid stratified serum diagnostics via ATR-FTIR spectroscopy

JR Hands, G Clemens, R Stables, K Ashton, A Brodbelt, C Davis, ...
Journal of neuro-oncology 127 (3), 463-472

Using Fourier transform IR spectroscopy to analyze biological materials

MJ Baker, J Trevisan, P Bassan, R Bhargava, HJ Butler, KM Dorling, ...
Nature protocols 9 (8), 1771

Global serum profiling: an opportunity for earlier cancer detection

A Sala, JM Cameron, PM Brennan, EJ Crosbie, T Curran, E Gray, P artin-Hirsch, IU Rehman, NJW Rattray, MJ Baker

Augmentation of FTIR spectral datasets using Wasserstein generative adversarial networks for cancer liquid biopsies

RG Hardy, G Antoniou, JJA Conn, MJ Baker, DS Palmer

Early economic evaluation to guide the development of a spectroscopic liquid biopsy for the detection of brain cancer

E Gray, JM Cameron, HJ Butler, MD Jenkinson, MG Hegarty, DS Palmer, ...
International Journal of Technology Assessment in Health Care 37

Stratifying brain tumour histological sub-types: the application of ATR-FTIR serum spectroscopy in secondary care

JM Cameron, C Rinaldi, HJ Butler, MG Hegarty, PM Brennan, ...
Cancers 12 (7), 1710

Exploring pre analytical factors for the optimisation of serum diagnostics: Progressing the clinical utility of ATR-FTIR spectroscopy

JM Cameron, HJ Butler, DJ Anderson, L Christie, L Confield, KE Spalding, ...
Vibrational Spectroscopy 109, 103092

Shining a light on clinical spectroscopy: Translation of diagnostic IR, 2D-IR and Raman spectroscopy towards the clinic

HJ Butler, JM Cameron, CA Jenkins, G Hithell, S Hume, NT Hunt, ...
Clinical Spectroscopy 1, 100003

Is infrared spectroscopy ready for the clinic?

D Finlayson, C Rinaldi, MJ Baker
Analytical chemistry 91 (19), 12117-12128

Optimised spectral pre-processing for discrimination of biofluids via ATR-FTIR spectroscopy

HJ Butler, BR Smith, R Fritzsch, P Radhakrishnan, DS Palmer, MJ Baker
Analyst 143 (24), 6121-6134

Biofluid infrared spectro-diagnostics: pre-analytical considerations for clinical applications

L Lovergne, P Bouzy, V Untereiner, R Garnotel, MJ Baker, G Thiéfin, ...
Faraday discussions 187, 521-537

Investigating optimum sample preparation for infrared spectroscopic serum diagnostics

L Lovergne, G Clemens, V Untereiner, RA Lukaszweski, GD Sockalingum, ...
Analytical Methods 7 (17), 7140-7149

Highlighting attenuated total reflection Fourier transform infrared spectroscopy for rapid serum analysis

KM Dorling, MJ Baker
Trends in biotechnology 31 (6), 327-328

Recurrent neural networks for time domain modelling of FTIR spectra: application to brain tumour detection

G Antoniou, JJA Conn, BR Smith, PM Brennan, MJ Bakr, DS Palmer

Clinical Validation of a Spectroscopic Liquid Biopsy for Earlier Detection of Brain Cancer

JM Cameron, PM Brennan, G Antoniou, HJ Butler,...
Neurooncology Advances 4(1):vdac024

Clinical Spectroscopy: Lost in Translation?

JM Cameron, C Rinaldi, SH Rutherford, A Sala,...
Applied Spectroscopy

Rapid analysis of disease state in liquid human serum combining infrared spectroscopy and “digital drying”

A Sala, KE Spalding, KM Ashton, R Board, HJ Butler, TP Dawson, ...
Journal of Biophotonics 13 (9), e202000118

Biofluid diagnostics by FTIR spectroscopy: A platform technology for cancer detection

A Sala, DJ Anderson, PM Brennan, HJ Butler, JM Cameron, ...
Cancer letters 477, 122-130

Development of high-throughput ATR-FTIR technology for rapid triage of brain cancer

HJ Butler, PM Brennan, JM Cameron, D Finlayson, MG Hegarty, ...
Nature communications 10 (1), 1-9

Investigating pre‐ analytical requirements for serum and plasma based infrared spectro‐diagnostic

L Lovergne, J Lovergne, P Bouzy, V Untereiner, M Offroy, R Garnotel, ...
Journal of biophotonics 12 (12), e20190017

Biofluid spectroscopic disease diagnostics: A review on the processes and spectral impact of drying

JM Cameron, HJ Butler, DS Palmer, MJ Baker
Journal of biophotonics 11 (4), e201700299

Combining random forest and 2D correlation analysis to identify serum spectral signatures for neuro-oncology

BR Smith, KM Ashton, A Brodbelt, T Dawson, MD Jenkinson, NT Hunt, ...
Analyst 141 (12), 3668-3678

Attenuated total reflection Fourier transform infrared (ATR‐FTIR) spectral discrimination of brain tumour severity from serum samples

JR Hands, KM Dorling, P Abel, KM Ashton, A Brodbelt, C Davis, ...
Journal of biophotonics 7 (3‐4), 189-199